I have found my YubiKey quite nice for password sercurity, but I use it in a slightly different way. I use password-store, which is a git repository of GPG encrypted passwords. While I'm on my main laptop, which has Qubes, I can access passwords using a key stored in my keys vault using Qubes split GPG. Encrypted passwords are synced through SSH to my serwer. On my other computers, I can decrypt passwords with my YubiKey as a gpg smart card. This is probably way overcomplicated, but it works.