I feel that if you go the whole react and SPA route you should use the tool mostly used with that : grunt/gulp, npm/bower, browserify/webpack. Even MS is going this route the VS 2015 projects will use grunt/npm/bower in the starting template, don't expect to have updated Nugget package for all those JS lib you will use for so long. And the is no Nugget packages for most lib you will have to use with React. The only thing that make it interesting is for the initial render but I don't know if it is easy to set up.